In rare cases, hydrochlorothiazide and valsartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially valsartan 80 mg generic if you also have fever, unusual tiredness, or dark colored urine. Drinking alcohol can further lower your blood pressure and may cause side effects. If you need surgery, tell the surgeon ahead of time that you are using hydrochlorothiazide and valsartan.
